Monday

Di Chiara Brothers, Stefano Esposito - Get Out (Original Mix)



you know, if you happen to come across, any of the beast's or bacteria, from the previous posts, may i suggest you, "Get Out", A.S.A.P, and beat a hasty retreat, to decontamination/the shower unit as, standardz, hahahahaha, :) #edio

Anthony Hypster - Anatome (Original mix)



you know, there are even biological organism that can take over the control of the, "Anatome", (Anatomy, a study of the structure or internal workings of something), as well as the external, like a puppet maser, Zombie ant fungus (Ophiocordyceps unilateralis) Ants are great navigators, following highly efficient paths as they forage for food. But in the rain-forests of Thailand, Africa and Brazil, Camponotus leonardi ants get pulled off course by Ophiocordyceps unilateralis, a parasitic fungus (pictured above). A spore first infects an ant foraging on the rainforest floor, then spends 3-9 days developing inside its body. When the fungus is ready to complete its life cycle, it manipulates the worker to plod blindly away from safety, like a zombie. A study in 2009 found that the ants always went to similar locations: around 25 cm up a tree, in a spot with just the right amount of humidity for then fungus to grow. The ant then clamps down on a leaf with its mandibles, and dies. Within 24 hours, fungal threads emerge from the corpse. Finally, a stalk pushes out of the ant and begins raining spores onto the rainforest floor, where they can infect more ants. It's a bit like the chest-bursting scene from Alien, except that the ant is mercifully dead when the fungus explodes out of its head, Kamikaze horsehair worm (Paragordius tricuspidatus) One of these worms can grow up to a foot long, and look like a cooked piece of spaghetti. But to get to that point, it needs a house cricket or grasshopper to do its bidding. First, a tiny horsehair worm larva is eaten by the larva of another insect, such as a mosquito or mayfly. Once this emerges from the water, a cricket or grasshopper will snatch it up. Then the horsehair worm begins to develop inside the cricket in earnest. But the worm's final stage of development takes place in water. The cricket wouldn't normally swim, or even hang out near water, so the worm must get it there. By altering the functions of the cricket's central nervous system, the worm coerces it into jumping slap bang into the nearest body of water. The hapless cricket then drowns itself, allowing the horsehair worm to emerge and reproduce. From the outside, you wouldn't be able to tell if a cricket had been infected, but neurologically, the worm is in control. Ben Hanelt of the University of New Mexico in Albuquerque, who studies the worms, says he has seen a whopping 32 worms pushing themselves out of one luckless host, Castrator barnacles (Sacculina sp.) If you think making a cricket believe it can swim is impressive, this parasitic barnacle takes body-snatching to another level. A Sacculina barnacle enters a host crab by finding a chink in its claw joints. The barnacle sheds its hard shell and squeezes itself in. At this point it looks more like a slug than a typical barnacle stuck to the underside of a boat. It then sets up home, leeching off the crab's nutrients and turning it into the vehicle that will allow it to reproduce. Once fully-grown, the barnacle looks more like a soft, pulsating egg yolk. If the crab is female, Sacculina forces it to care for the millions of barnacle larvae as if they were her own. But if the crab is male, it will be feminised in order to do the same thing. Not only is it rendered infertile, it grows a larger abdomen to carry the barnacle's young, its gonads shrink, and it stops developing its fighting claws. Green-banded broodsac (Leucochloridium paradoxum) If you see a snail with two beautiful eye stalks, pulsating with emerald- and olive-green stripes and dappled with charcoal grey flecks capped off with a maroon dab, be impressed. You're not just looking at a pimped-out snail, you're looking at a snail infected with a parasitic flatworm. The green-banded broodsac first squirms its way into the stalks of the snail, so that they look like juicy, pulsing, brightly-coloured caterpillars. This is just the kind of snack nearby birds are in the mood for. Then the worm manipulates the snail's behaviour. In 2013, Wanda Wesolowska and Tomasz Weslowski of Wroclaw University in Poland found that the infected snails behaved differently from their apparently non-infected counterparts. They positioned themselves in more exposed and better-lit places, situated higher in the vegetation. This probably makes the snails more conspicuous for foraging birds. Once eaten by the bird, the worm can reproduce, and the cycle continues. Ladybird parasite (Dinocampus coccinellae) This wasp needs a host that will protect its eggs from potential predators. So what better bodyguard than an insect with markings that suggest danger? Ladybirds may seem like the stuff of cartoons and cute lunchboxes, but they can take care of themselves. When disturbed they emit a disgusting poison, and their hard shell with its bright red and black spots warns off predators. But they don't stand a chance against the parasitic wasp, which leaves behind a single egg with one sting. After the wasp egg hatches, the larva chews through the ladybird's internal tissues before bursting through the abdomen to spin a cocoon between its legs. The ladybird is now a "bodyguard", standing guard over the cocoon. Still alive despite everything, it will thrash and twitch its limbs if a predator approaches. It's not clear why it behaves like this, but it may be triggered by venom left by the larva. Rather unexpectedly, a 2011 study found that a quarter of the zombie ladybirds survive the assault. Emerald cockroach wasp (Ampulex compressa) The emerald cockroach wasp has a metallic body that glows emerald with bright crimson markings on two of its legs. Found in the tropical regions of Asia, Africa and the Pacific islands, it is a beautiful insect, but pity the cockroach that crosses its path. It is one-sixth the size of a roach, but that doesn't stop it. First it delivers a simple paralysing sting. Then it hijacks the roach's mind, injecting an elixir of neurotransmitters into its brain. This turns the roach into a helpless zombie. After a quick suck of recharging roach blood, the wasp chews off the roach's antennae and leads it to its nest like a dog on a lead. There it lays its eggs on the roach's abdomen, and barricades it in with pebbles. But the hapless roach doesn't even try to escape, even though it physically could. It just sits there submissively, as the wasp larva eats it alive. Finally the adult wasp bursts out of the cockroach's remains. Toxoplasmosis (Toxoplasma gondii) This single-celled creature is perhaps the most famous of all host-manipulating parasites, perhaps because it operates close to home. It mainly infects rats and mice, in order to be eaten by a cat so that it can reproduce.Infected rats and mice lose their fear of the smell of cats, according to a 2007 study. Instead, they become attracted to a pheromone in the cats' urine. The animal becomes less likely to hide under the floorboards and more likely to sniff around its feline predators, putting the parasite on course for its ultimate destination: the cat's stomach.  Between 30 and 60% of people are infected by T. gondii. But it's less clear that the parasite affects human behaviour. In 2006 Kevin Lafferty of the US Geological Survey in Santa Barbara, California found some evidence of personality changes in people infected by the parasite. So far this is only a correlation, which is far from conclusive. Nevertheless, Lafferty says: my money is on cause and effect, Toxoplasmosis is also unusually common in people with schizophrenia, but again it's not clear what that means or how significant it is. "Schizophrenia is a complicated syndrome, perhaps with multiple causes," says Lafferty. He adds that there are plenty of infected people that don't have schizophrenia, and plenty of people with schizophrenia who aren't infected. Still, I am comfortable in saying that Toxoplasma is a correlated risk factor for schizophrenia. Rabies viruses You might not think of a virus like rabies as a parasite, but to a biologist that's exactly what they are. "I would call rabies and flu parasites, because they generally reduce the fitness of their host, or benefit at the expense of their host," says Levi Morran of Emory University in Atlanta, Georgia. Rabies is one of the most frightening parasites, because it seems to blur the line between humans and animals. The virus is spread through saliva, usually from a scratch or bite. It makes animals – usually dogs and bats, and occasionally humans – more aggressive, compelling them to spread the virus through biting and scratching. Rabies manifests itself with a wide range of neurological signs, including changes in behaviour but also loss of motor control, says parasite expert Andres Gomez of ICF International in Washington, DC. The latter sometimes include difficulties with swallowing that eventually lead to hunger, hypoglycaemia, and dehydration, Supposedly, it creates a fear of water, but this is a myth. Patients have involuntary spasms when trying to drink and later when presented with water, says Gomez. But it's not fear.  Influenza virus Yes, that's the flu. In 2010 Chris Reiber of Binghamton University in New York and her colleagues found evidence that the influenza virus makes people more sociable. They found that people given a flu vaccine interacted with significantly more people, and in significantly larger groups, in the 48 hours after being exposed, compared with the 48 hours before. The infected hosts were more likely to head out to bars and parties. It's only one study, and quite a small one, but it does make a certain sinister sense. It would benefit the virus if its host passed it on to as many people as possible, before the symptoms started and they became bedridden. Schistocephalus solidus Parasites are everywhere. Most species will be living with more than one parasite, and even parasites may have their own parasites. So in some cases, a host may be carrying multiple parasites with different agendas, who must battle for control of the host. This is particularly likely if one parasite is ready to move onto another host, but the other isn't. To see this happening, Nina Hafer and Manfred Milinski of the Max Planck Institute for Evolutionary Biology in Ploen, Germany infected small crustaceans called copepods (Macrocyclops albidus) with multiple tapeworms (Schistocephalus solidus). These tapeworms ultimately need to move onto a fish host called a stickleback, and to get there they manipulate the copepod's behaviour. It becomes more active, and thus more likely to be spotted and eaten by a stickleback. If two tapeworms were both ready to move hosts, their effect on the copepod's behaviour was even stronger, suggesting they were working together. However, if an older tapeworm that wanted to leave was sharing the host with a younger tapeworm that wasn't yet ready, the host copepod still became active. It was as if the younger tapeworm wasn't there. Hafer and Milinski argue that the older tapeworm was effectively sabotaging its younger competitor. talk about a brutal sibling rivalry as, standardz, hahahahaha, :) #edio

FAC3OFF - Outbreak (Original Mix)



you know, there is so much fuckery, it could be done via a biological, "Outbreak", Zombies have dominated science fiction for years. But they don't actually exist, right? Wrong. There are several real-life diseases that could make you act like a zombie. If we're going to talk about zombie-like diseases, we first need to decide what the symptoms of being a zombie actually are. Obviously, the big one - you know, being literally, actually (un)dead - isn't something with any real world medical parallels, so we'll just have to restrict ourselves to diseases that make people act like the walking dead. That would include traits like rotting or dead flesh, a trance-like state that would rob people of any sign of higher cognitive function, an inability to communicate in anything more than moans and grunts, a slow, shuffling gait, and (if we're really lucky) a taste for human brains, or at the very least the desire to bite people. Is there a single disease that can do all that? Well...no. But there are a whole heap of diseases that can do quite a few of those, and that's plenty terrifying enough. Indeed, let's start with the most horrific possibility of them all:Sleeping sickness, Sleeping sickness is the stuff nightmares are made of. The headline of this BBC News article from 2005 pretty much says it all: "The disease that makes people zombies." Prevalent in Africa, sleeping sickness is caused by the parasite Trypanosoma brucei and transmitted by the tsetse flyInterviewed for the BBC News piece, Professor Sanjeev Krishna of the University of London and a doctor at a hospital in Lucala, Angola, explained the horrible progression of the disease: At first it will cause headaches, aching muscles and maybe itching. But in the late stages, when the parasites have invaded the brain, the signs become more obvious and ominous. Victims find it hard to concentrate. They become irritable, their speech is slurred and they stop eating. Their daily rhythm becomes disrupted to such an extent that they can't sleep at night and find it almost impossible to stay awake during the day. It even becomes very hard for them to do simple mental tasks, such as drawing a straight line. This is an infection that carries nightmarish qualities, reducing many of its victims to a zombie-like state before they go into a coma and die. Those that do survive can be left with irreparable brain damage. Worse, there are still no vaccines or ways to prevent infection occurring once the tsetse fly bites a person. Even the available treatments are - to be charitable - less than perfect. Melarsoprol is one of the few treatments available (and that rather dubiously assumes that the average infected person has access to any medical care), but it's over fifty years old and contains enough arsenic to kill 1 in 20 people that are treated with it. And even if a patient survives the ordeal, they remain at risk of contracting the disease again later. About 50,000 to 70,000 people die of sleeping sickness every year, although Krishna suspected that estimate was actually much too low. In Uganda, one in every three people is at risk of getting the disease, and some sixty million people remain under constant threat. So then, there are about 50,000 examples of the walking dead each year, although (perhaps mercifully) they don't remain walking for very long. Thankfully, there is some hope. The genome of Trypanosoma brucei was sequenced this April, and it is currently being compared to another strain of the parasite that only affects cows. Researchers at the Sanger Institute who carried out the sequencing hope this comparison will yield hugely useful data on just why one strain infects humans and the other doesn't. This could pave the way for new drugs that would greatly reduce the mortality of sleeping sickness and hopefully decrease the incidence of the most severe, zombie-like symptoms in the afflicted. Rabies, There isn't a disease, be it mental or physiological, that makes people want to eat other people, at least none as currently recognized by medical science. (Cannibalism isn't considered a mental illness in its own right, but rather as a part of a larger web of psychoses.) There are certain culture-specific mental conditions - Wendigo psychosis, observed in certain native American peoples, is one of the better examples - that make people think they are turning into cannibals, but that's about it, Still, rabies can, under certain conditions, approximate some of the conditions of the zombie lust for brains. The rabies virus causes massive inflammation, or swelling, of the brain, and it's most often transmitted by bites from infected animals. About 55,000 people die annually from rabies, with almost all of these deaths occurring in Asia and Africa. Although vaccines do exist (indeed, it was Louis Pasteur's successful treatment of a rabies-infected child that brought us into the modern age of vaccinations), they have to be administered before the onset of symptoms if the patient is to survive. Again, the symptoms of rabies sound rather like those of the walking dead: full or partial paralysis, mental impairment, agitation and strange behavior, mania, and finally delirium. It takes a bit of cherry-picking of symptoms, but one could put together a rabies patient with an inability to think clearly or communicate, difficulty walking, and manic aggression that takes the form of frequent attacks on humans. Although such a zombie-esque sufferer is medically possible, such a hypothetical patient is apparently really, really unlikely. Human-to-human transmission of rabies is incredibly rare, and it almost always occurs thanks to insufficient background tests before organ transplants. So there aren't very many, if any, people going around biting other people. But, to be fair, rabid animals do act a whole lot like extras in 28 Days Later, with uncharacteristic behavior, aggression leading to attacks, and an apparent loss of all reason. Until human rabies manifests itself more like animal rabies - and it's not something I'm exactly hoping for - that's about the closest we're getting to real world brain-hungry zombies. Necrosis, Those of you who are up on your Greek roots already know where we're going with one: necrosis is death, specifically those of individual groups of cells before the organism as a whole dies. This isn't technically a disease but rather a condition with a lot of different possible causes. Cancer, poison, injury, and infection are all possible causes of premature cell death. If we're being super-literal about what the walking dead really are, then a patient with necrotic tissue is maybe the closest equivalent. After all, a patient suffering from necrosis technically is partially dead, albeit still very much alive in all the important areas (the brain, the heart, and the rest of the vital organs, for a start) that we generally associate with the living. Whatever its external (or, in the case of cancer or infarction, internal but extraordinary) cause, necrosis triggers a series of event that can lead to even greater negative effects outside the affected area. The dead tissue stops sending signals to the nervous system, and necrotic cells can release dangerous chemicals that hurt nearby, still healthy cells. If the lysosome membrane inside the cells is damaged, enzymes can be released that can also harm surrounding cells. This chain reaction can cause the necrosis to spread (and if it spreads over a great enough area, it becomes gangrene) and can ultimately be fatal. The only way to cure the condition is through a process known as debridement, which is simply the removal of necrotic tissue. If the dead area is too large, this may require amputation. If there is any sort of bright side to all this - and I'm not sure there is, but I'll put my Pollyanna hat on and try my best - at least necrosis isn't contagious, meaning it's not the sort of thing that could spur a faux-zombie outbreak. Of course, a sudden wave of hyper-aggressive, necrosis-spreading spiders or snakes? That might be another matter entirely. Dysarthria, Let's take a bit of a break and talk about something relatively less serious. Relatively being very much the key word there, We've talked about possible causes of zombie-like trances, cell death, and hyper-aggression. What about something a little more innocuous, like the iconic moans and grunts of the oncoming zombie horde? What could cause that?Well, the best real-world equivalent is probably dysarthria, which is a disorder affecting the motor controls of human speech. Dysarthria is particularly appropriate because it's neurological in its origins, which ties in with the brain-based aspects of zombie lore. There are a lot of different causes of dysarthric speech, but all are characterized by a malfunction in the nervous system that makes it difficult to control the tongue, lips, throat, or lungs. This in turn causes difficulty in articulation, which can take the form (among many possible man, ifestations) of an inability to communicate in more than unintelligible noises. The condition can be brought on by traumatic brain injury, metabolic diseases like Lou Gehrig's or Parkinson's, or a stroke, all of which lead to a loss of control over the vocal muscles. Possible affected areas include the ability to regulate the volume of speech, the ability to create the proper inflection, and, most importantly for our purposes, the ability to create the correct sounds of speech. To be sure, in and of itself dysarthria is not a particularly zombie-ish condition. However, coupled with any of the other diseases on this list, it gets you frighteningly close to a real approximation of the sight and sound of the walking dead. Leprosy, Both zombie folklore and leprosy have a long, long history. Armies of the flesh-eating undead can be traced all the way back to the roughly tenth century BCE Akkadian work The Epic of Gilgamesh, which drew on earlier Sumerian mythology and was one of the first substantial written works in human history. Cases of leprosy have been reported going back some four thousand years throughout Eurasia and northern Africa, including China, India, and Egypt. Considering a common feature of zombies is their rotting flesh and decaying body parts, it would seem like leprosy and its similar-sounding symptoms would be a natural inspiration for such stories. Well...sort of. The truth is (as usual) rather more complicated. First of all, it's a myth that leprosy causes body parts to rot away and fall off - indeed, there really aren't any diseases that can actually make limbs fall off (although, as discussed earlier, necrosis can necessitate the amputation of dead limbs). Leprosy can cause damage and numbness in its victims, which could cause a slow, shuffling walk that might have inspired the gait that we associate with zombies. The main external symptom of leprosy is the outbreak of extensive skin lesions, which gives the skin a diseased, decaying appearance not unlike that of the common conceptions of zombies. Fortunately, leprosy is pretty much under control at this point, certainly compared to sleeping sickness. Over 95% of people are naturally immune to the disease, and over fifteen million people have been cured of the disease in the last two decades. It's a remarkable turnaround for once of the most feared and stigmatized diseases in human history - indeed, for centuries leprosy evoked the same kind of irrational dread that we might now feel towards the dead rising from the graves en masse, ready to devour our brains. Although there are definitely a few connections to be drawn between the symptoms of leprosy and the supposed traits of zombies, maybe the most fascinating overlap can be found in the story recounted in John Tayman's 2007 book The Colony: The Harrowing True Story of the Exiles of Molokai. As the Zombie Research Society reports, the book describes how the lepers at the Hawaiian colony were literally treated like they were the walking dead. The leprosy patients were judged legally dead, their spouses were granted immediate divorces on the grounds they were basically widows anyway, and their wills were executed. The patients were then banished to a remote island where they were left to die, although some survived on the island for decades. This tragic part of Hawaiian history - a story with plenty of echoes elsewhere - is pretty close to how one might expect society would actually treat zombies if they existed instead of attempting to cure them as, standardz, hahahahahaha, :) #edio

Arnaldo Miranda - Confused (Original Mix)



you know, they usually snap out of it, after the event all dazed and, "Confused", there are multiple ways of inducing a zombie like state as, standardz, hahahahaha, :) #edio

Arnaldo Miranda - Confused (Original Mix)



you know, they usually snap out of it, after the event all dazed and, "Confused", there are multiple ways of inducing a zombie like state as, standardz, hahahahaha, :) #edio

Maxdal - The Magic (Gaga Remix)



you know, most people don't even realise, when they have been under the influence of, "The Magic", of the dark-side of the force, they just act on impulse, not thinking of consequences or its effects, it's a kind of auto pilot response, there yet not, like the lights are on, but nobody's home as, standardz, hahahahahaha, :) #edio

Black Roof - Resumption (Original Mix)



you know, i'm totally right we need a swift, "Resumption", of family values and a social reform as, standardz, hahahahahaha, :) #edio

Serial Thrilla - Ain't A Game (Original Mix) [Tasty Recordings Digital]



you know, our collective health and welfare, of us and our environment, should be the worlds highest priority, if the environment cannot support life, the rest is irrelevant, And my life, "Ain't A Game", theres is no chance i'm letting someone else, roll the dice for me on my fate as, standardz, hahahahahaha, :) #edio

Robosonic & Klangkuenstler - Nuts



you know, you have to rest, even if it's just to meditate and close your eyes, if you don't take some form of rest it can make you go, "Nuts", it can even alter, your natural biorhythms, (http://www.dtic.mil/docs/citations/AD0732872 Ten adult males were subjected to partial sleep deprivation experiments, in order to study the effects of progressive sleep deprivation, on the basic biological rhythms underlying performance on signal detection tasks, and to assess the value of using change in biological rhythms, as an objective measure of human response to such types of stress. The data obtained were subjected, to a power density spectral analysis, with a program based upon the Fast Fourier Transform. The results show, that signal detection measures, response latency, and heart rate are all highly sensitive in reflecting progressive loss of performance capability. Power spectral data also show changes as a function of sleep deprivation, indicating that one feature of this type of stress, may be an alteration of basic human biorhythms), which can effect your dna as well as mental and physical state as, standardz, hahahahahaha, :) #edio

Charlotte de Witte - Actually (Original Mix)



you know, it could, "Actually", be beneficial to go later in the day, it allows me to rest a little, as let's face it, i need to sometimes with all that i do as, standardz, hahahahaha, :) #edio

Pierre Deutschmann I Lose A Dream



you know, it may not be a bad thing, you see, when i have to travel, i can never sleep, there's even less chance than normal, "I Lose A Dream", and end up, having to jump up at o.m.g it's early o' clock, run around in a panic forget to eat and then get on a very high speed train, by the time i arrive it feels like i left my stomach on the platform, so in an attempt to doge it, i came up with traveling later in the day, but a day early as, standardz, hahahahahaha, :) #edio

HOUSE: Devon James & Ant LaRock - Ghetto Style [SOUP NYC]



well peep's, it's just been brought to my attention, that i have a train to catch tomorrow, as i stupidly tried to plan around the fuckery, to get a jump, "Ghetto Style", on my Nemesis, and ended up blindsiding myself, as i didn't really need to be there, until the day after, oh well, at least it will be dealt with quicker as, standardz, hahahahahaha, :) #edio
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